We would consider TSW to be a very serious condition.

It leaves your skin in such a vulnerable and fragile state and you can quickly become seriously ill during the withdrawal period. It is not for the faint hearted. You may find yourself becoming incapacitated as your skin cycles through the withdrawal process. It can become hard to move without being in pain and many find themselves stuck in bed, or glued to the sofa for days on end just trying to find some level of comfort.

Your skin is the largest organ in your body and TSW puts the whole thing into crisis mode. There is a high chance you will experience local skin infections so it is important to keep these areas clean. Be sure to check for signs of more serious infections and sepsis as these are both possible with open wounds. 

There is a chance you will be too ill to do normal things and retain your independence. Many find they have to take a few weeks or even months off work during the hardest period of TSW.